English: Migration of interneurons in the embryonic cerebral cortex. E16 cerebral cortex from Dlx5/6-CIE mice were repeatedly imaged at 8 minute intervals using a Zeiss inverted microscope attached to a PASCAL confocal laser scanning system and a live cell incubation chamber. These images were compiled as AVI movie files to illustrate the extent of different modes of interneuronal migration in the developing cerebral wall. Most of the interneurons migrate tangentially from the ganglionic eminence towards cortex and in radial directions towards the cortical plate or ventricular surface. A significant number of interneurons also migrate in cortex → ganglionic eminence direction. White arrows point to general direction of different cerebral cortical regions. GE, ganglionic eminence; CX, cortex; VS, ventricular surface. Time length = 11.2 hrs.